- Product Details
Keywords
- 139504-50-0
- Maytansinoid DM1
- 98%+, DM1
Quick Details
- ProName: Mertansine, DM1
- CasNo: 139504-50-0
- Molecular Formula: C??H??ClN?O??S
- Appearance: White to off-white powder
- Application: Cytotoxin, Microtubulin inhibitor
- DeliveryTime: In stock
- Port: Shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: Long term storage at 2-8℃.
- Transportation: Transportation condition: shipping at ...
- LimitNum: 0 Metric Ton
Superiority
Product in stock
Details
Mertansine is a tubulin inhibitor, meaning that it inhibits the assembly of microtubules by binding to tubulin (at the rhizoxin binding site). Mertansine (DM1) is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).