China (Mainland)
DM4 CAS NO.796073-69-3
- Min.Order: 0 Metric Ton
- Payment Terms: T/T
- Product Details
Keywords
- 796073-69-3
- Maytansinoid DM4
- 98%+, DM1
Quick Details
- ProName: DM4
- CasNo: 796073-69-3
- Molecular Formula: C??H??ClN?O??S
- Appearance: White to off-white powder
- Application: Cytotoxin
- DeliveryTime: In stock
- PackAge: As per request
- Port: Shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: Store in a tight container at -20℃
- Transportation: Shipping at room temperature if less t...
- LimitNum: 0 Metric Ton
Superiority
Product in stock
Details
DM4 is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody drug conjugate. It is a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death.